Cardiology
Valvular Heart Disease
Cardiology

Valvular Heart Disease

AS, AR, MS, MR — diagnosis and surgical thresholds.

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Aortic stenosis

  • Age <70: bicuspid valve; ≥70: senile calcific
  • Severe AS: late-peaking systolic murmur + soft A2 + narrow pulse pressure + pulsus parvus et tardus
  • Symptomatic severe AS or LVEF <50% → valve replacement (TAVR or surgical)
  • Medical therapy does NOT fix obstruction
  • Avoid vasodilators in severe AS

Aortic regurgitation

  • Marfan + AR from root dilation → risk of dissection
  • Early diastolic decrescendo murmur
  • Widened pulse pressure; water-hammer pulse
  • Annual echo; replace root when >5 cm
  • BB or ARB to slow dilation

Mitral disease

  • MS: opening snap + mid-diastolic murmur; severe (valve area <1.0) + symptoms → balloon valvotomy
  • Chronic MR: regurgitant flow → LV dilation; surgical repair when symptoms or EF <60%
  • Post-MI functional MR (improves with diuretics) vs papillary muscle rupture (does NOT improve, requires surgery)

Rheumatic fever prophylaxis

  • No carditis: 5 years or until age 21 (whichever longer)
  • Carditis without residual disease: 10 years or until age 21
  • Carditis with persistent valvular disease: 10 years or until age 40
  • Benzathine penicillin G IM every 4 weeks

Other vascular conditions

  • Coarctation: arm-leg BP difference + weak femoral pulses → echo to confirm
  • Young cryptogenic stroke + DVT → bubble study echo for PFO (paradoxical embolism)
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