Notes
Cardiology
Valvular Heart Disease
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Cardiology
Valvular Heart Disease
AS, AR, MS, MR — diagnosis and surgical thresholds.
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Aortic stenosis
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Age <70: bicuspid valve; ≥70: senile calcific
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Severe AS: late-peaking systolic murmur + soft A2 + narrow pulse pressure + pulsus parvus et tardus
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Symptomatic severe AS or LVEF <50% → valve replacement (TAVR or surgical)
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Medical therapy does NOT fix obstruction
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Avoid vasodilators in severe AS
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Aortic regurgitation
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Marfan + AR from root dilation → risk of dissection
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Early diastolic decrescendo murmur
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Widened pulse pressure; water-hammer pulse
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Annual echo; replace root when >5 cm
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BB or ARB to slow dilation
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Mitral disease
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MS: opening snap + mid-diastolic murmur; severe (valve area <1.0) + symptoms → balloon valvotomy
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Chronic MR: regurgitant flow → LV dilation; surgical repair when symptoms or EF <60%
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Post-MI functional MR (improves with diuretics) vs papillary muscle rupture (does NOT improve, requires surgery)
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Rheumatic fever prophylaxis
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No carditis: 5 years or until age 21 (whichever longer)
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Carditis without residual disease: 10 years or until age 21
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Carditis with persistent valvular disease: 10 years or until age 40
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Benzathine penicillin G IM every 4 weeks
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Other vascular conditions
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Coarctation: arm-leg BP difference + weak femoral pulses → echo to confirm
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Young cryptogenic stroke + DVT → bubble study echo for PFO (paradoxical embolism)
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