EKG
RV strain, PE, and cor pulmonale
EKG

RV strain, PE, and cor pulmonale

EKG findings of acute and chronic RV overload — when to suspect what.

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Acute RV strain (PE)

  • Sinus tachycardia (most common)
  • S1Q3T3 (classic but only ~20%)
  • T-wave inversions V1–V4
  • New incomplete or complete RBBB
  • Right axis deviation

Cor pulmonale (chronic RV pressure overload)

  • P pulmonale: tall (>2.5 mm) peaked P wave in II — RA enlargement
  • RVH: R/S ratio >1 in V1, right axis deviation
  • Low voltage in limb leads (COPD with hyperinflation)

Diagnosis & management of PE

  • Low pretest probability (Wells score 0–4) → D-dimer; negative D-dimer rules out
  • High pretest (Wells >4) or positive D-dimer → CT-PA (V/Q if contrast contraindicated)
  • Massive PE (hypotension/shock) → systemic thrombolysis (tPA)
  • Submassive PE (RV strain on echo or CT, +troponin, normotensive) → consider catheter-directed thrombolysis vs anticoagulation alone
  • Stable PE → DOAC (apixaban or rivaroxaban) for ≥3 mo (longer if unprovoked)

High-yield pearls

  • PE prophylaxis missed → submassive PE post-op is a common board scenario
  • Pregnant patient with suspected PE: V/Q scan preferred over CT-PA (lower radiation to breasts); LMWH for treatment (NO warfarin or DOAC)
  • Echo finding of McConnell's sign (RV free wall akinesia with preserved apex) is highly specific for acute PE
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