OB/GYN
Antepartum Bleeding — Differential
OB/GYN

Antepartum Bleeding — Differential

Placenta previa vs abruption vs uterine rupture vs vasa previa.

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Quick differentiator rules

  • Painful bleeding = mom's problem (abruption, rupture)
  • Painless bleeding = baby's problem (previa, vasa previa)
  • Contractions present? Yes → abruption; No → rupture or previa
  • Loss of fetal station → uterine rupture until proven otherwise
  • Bleeding right after ROM + fetal bradycardia + stable mom → vasa previa

Placenta previa management

  • Confirm with transabdominal US
  • NEVER digital cervical exam (risk of severe hemorrhage)
  • Pelvic rest (no intercourse)
  • Scheduled C-section at 36–37 weeks
  • If actively bleeding hemodynamically unstable → emergent C-section

Placental abruption management

  • Stabilize mother (IV fluids, transfusion as needed)
  • Continuous fetal monitoring
  • Delivery if maternal/fetal instability — vaginal if stable, C/S if not
  • DIC workup (fibrinogen, platelets, PT/PTT)

Uterine rupture management

  • Emergent ex-lap + C-section (NO time for imaging)
  • Strongest RF: prior cesarean (especially classical incision)
  • TOLAC carries small but real rupture risk

Vasa previa management

  • If diagnosed antenatally on US/Doppler: scheduled C-section at 34–37 weeks
  • If ROM occurs + bleeding: emergent crash C-section
  • Fetal exsanguination within minutes

Placental adherence (accreta spectrum)

  • Accreta: adherent to myometrium
  • Increta: invades myometrium
  • Percreta: invades through into bladder
  • RFs: prior C/S + previa overlying scar
  • Manage with planned cesarean hysterectomy

Antepartum bleeding patterns

ConditionPainBleedingUterusContractionsKey clue
Placenta previaPAINLESSBright redSoftAbsentPainless bleeding + soft uterus + previa on US
Placental abruptionPAINFULVariable (often dark)RIGID/tetanicPresentHTN, cocaine, trauma; risk of DIC
Uterine rupturePAINFULVariableVariableContractions CEASEPrior C/S + loss of fetal station
Vasa previaPAINLESS (after ROM)Fetal bloodSoftBleeding immediately after ROM + sudden fetal bradycardia, mom stable

High-yield pearls

  • Loss of fetal station during labor = uterine rupture
  • Painful + rigid uterus + cocaine/HTN = abruption
  • Painless bright-red + soft uterus = previa (NEVER do digital exam)
  • After ROM + fetal bradycardia + stable mom = vasa previa
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